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Gene Therapy & Viral Vectors

Move fast without losing the thread.

Gene therapy and viral vector teams are constantly learning across upstream, downstream, and analytical work. Invert helps keep that process history organized from the start, so your team can understand what changed, what worked, and what to do next.

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The problem

Keep the full process story together.

Gene therapy programs move quickly, especially when teams are developing AAV, lentiviral, or other viral vector processes. Serotypes, feeds, transfection conditions, purification strategies, and analytical methods can all change as teams work toward a process that is productive, scalable, and ready for IND.

This creates a lot of hard-earned process knowledge that is easy to lose. Upstream data, downstream data, and analytical results often live in separate places. Comparing vector genome titer, infectious units, full/empty capsid ratio, purity, and yield across runs can take days of manual work, especially when the process is changing or a CDMO becomes involved.

Invert gives your team one place to connect the full story of your process: from triple transfection and bioreactor conditions, through TFF and ÄKTA purification, to ddPCR, titer, purity, and yield. With the right data foundation in place, it becomes much easier to answer questions, prepare for tech transfer, and learn from every run as your program scales.

Capabilities

Easily answer questions like:

  • Why is titer dropping in the lentiviral suspension process over the last 8 runs? Is it drift or a step-change?
  • What’s the relationship between cell density at transfection and genome-containing particles per mL for AAV9?
  • Summarize all the harvest timing experiments we’ve run and tell me the optimal harvest window for yield vs quality tradeoff.
  • Show me which upstream parameters predict downstream step yield losses for the adeno program.
  • Build a side-by-side of the three TFF conditions we tested for AAV concentration and show recovery, shear markers, and aggregation.

How we deliver

We help your team keep the full process story together.

01

Connect the full process

Invert brings upstream, downstream, and analytical data into one organized layer. Your team can understand how process conditions connect to final outcomes without rebuilding the same analysis every time.

02

Keep up as your process evolves

Gene therapy development changes quickly as teams test new conditions, scales, and process strategies. Invert keeps your data structure flexible, so your team can keep learning without the pipeline breaking every time the process evolves.

03

Carry context forward

When programs move to a CDMO, scale up, or approach IND, the details behind each process decision matter. Invert keeps that history traceable and easy to access, so your team can answer questions without starting from scratch.

Explore the product

The product behind every vector.

Foundation

One connected record from transfection through release.

Bioreactor, TFF, ÄKTA, ddPCR, titer, and purity data in one traceable layer that adapts as serotypes, feeds, and purification strategies change.

Explore Foundation Intelligence

The hard questions, answered before the next run.

A bioprocess-native AI teammate that compares runs across serotypes, feeds, and purification strategies — and carries the context forward to CDMO and IND.

Explore Intelligence
Case study · Pre-clinical advanced therapy
3.5 mo
ahead of IND plan
4 weeks
to go live
<20 min
per week on data prep, from 5–10 hours
Read the full case study

Move fast. Keep the thread.

Bring a vector transfer question, a comparability gap, or a process that’s been iterating faster than the data can keep up. In 30 minutes we’ll show you what your program looks like on one connected record.

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